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Conditional Expression of Fibroblast Growth Factor-7 in the Developing and Mature Lung

1 Apr 2000

Abstract excerpt

Effects of fibroblast growth factor-7 (FGF-7) on lung morphogenesis, respiratory epithelial cell differentiation, and proliferation were assessed in transgenic mice in which the human FGF-7 cDNA was controlled by a conditional promoter under the direction of regulatory elements from either the human surfactant protein-C (SP-C) or rat Clara cell secretory protein (ccsp) genes. Expression of FGF-7 was induced in...

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PMID: 10766812
DOI: 10.1074/jbc.275.16.11858

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