Article
A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila.
Development (Cambridge, England) - 1 Apr 2009
Webb Rebecca L, Zhou Meng-Ning, McCartney Brooke M
Abstract excerpt
The rearrangement of cytoskeletal elements is essential for many cellular processes. The tumor suppressor Adenomatous polyposis coli (APC) affects the function of microtubules and actin, but the mechanisms by which it does so are not well understood. Here we report that Drosophila syncytial embryos null for Apc2 display defects in the formation and extension of pseudocleavage furrows, which are cortical actin...
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