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Article

Diaphanous-Related Formin 2 and Profilin I Are Required for Gastrulation Cell Movements

20 Oct 2008

Abstract excerpt

Intensive cellular movements occur during gastrulation. These cellular movements rely heavily on dynamic actin assembly. Rho with its associated proteins, including the Rho-activated formin, Diaphanous, are key regulators of actin assembly in cellular protrusion and migration. However, the function of Diaphanous in gastrulation cell movements remains unclear. To study the role of Diaphanous in gastrulation, we...

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PMID: 18941507
DOI: 10.1371/journal.pone.0003439

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