Article
Association of HLA-A in autoimmune myasthenia gravis with thymoma.
Journal of neuroimmunology - 29 May 2009
Vandiedonck Claire, Raffoux Colette, Eymard Bruno, Tranchant Christine, Dulmet Elisabeth, Krumeich Sophie, Gajdos Philippe, Garchon Henri-Jean
Abstract excerpt
We investigated an association of the HLA-A locus in 78 French Caucasian patients with autoimmune myasthenia gravis (MG) and thymic epithelial tumours. The largest effect was a protection associated with HLA-A02 in MG patients with a B2 type thymoma (OR=0.323, 95% CI: 0.113-0.756, P=0.00041). The frequency of HLA-A25 was also increased in the whole group of patients (OR=3.62, 95% CI: 1.62-7.08, P=0.0041). Our...
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