Article
Trans-encoded DQ alpha beta heterodimers confer susceptibility to myasthenia gravis disease.
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie - 1 Jul 1993
Khalil I, Berrih-Aknin S, Lepage V, Loste M N, Gajdos P, Hors J, Charron D, Degos L
Abstract excerpt
Myasthenia gravis (MG) is an autoimmune disease associated with thymic abnormalities (hyperplasia and thymoma). With classical typing method, no clear association was observed between HLA class II and MG disease except in a subgroup of patients with hyperplasia. The aim of our work was to investigate a possible correlation between HLA class II alleles and MG disease using molecular typing which was proved to be...
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