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Article

Myasthenia gravis patients with thymus hyperplasia and myasthenia gravis patients with thymoma display different HLA associations.

Tissue antigens - 1 Feb 1991

Spurkland A, Gilhus N E, Rønningen K S, Aarli J A, Vartdal F

Abstract excerpt

Thirty myasthenia gravis (MG) patients (9 with thymoma, 12 with thymus hyperplasia and 9 with thymic atrophy) and 181 Norwegian healthy controls were serologically typed for HLA-A, -B and -DR antigens and genomically typed for HLA-DQA1 and HLA-DQB1 alleles by probing in vitro amplified DNA with sequence-specific oligonucleotides. In patients with thymus hyperplasia the frequency of the DQB1*0201 allele was...

Topics

Alleles
Antigens, Neoplasm
Genetic Predisposition to Disease
HLA Antigens
Humans
Hyperplasia
Myasthenia Gravis
Oligonucleotide Probes
Thymoma
Thymus Gland
Thymus Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2057938
DOI: 10.1111/j.1399-0039.1991.tb01851.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2057938-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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