Article
HLA and age of onset in myasthenia gravis.
Neuromuscular disorders : NMD - 1 Jul 2017
Santos Ernestina, Bettencourt Andreia, da Silva Ana Martins, Boleixa Daniela, Lopes Dina, Brás Sandra, Costa Paulo Pinho E, Lopes Carlos, Gonçalves Guilherme, Leite Maria Isabel, da Silva Berta Martins
Abstract excerpt
The aetiology of MG is unknown, but both genetic and environmental factors are important. Over the years association of MG with Human Leucocyte Antigens (HLA) has been described in different populations. We investigated a possible association between HLA-DRB1 alleles and age of onset in MG. One hundred and fourteen MG patients (82 females) and 282 control individuals (CP) were studied. Patients were classified...
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