Article
Interleukin-1beta gene (IL-1beta) polymorphisms (SNP -511 and SNP +3953) in thyroid-associated ophthalmopathy (TAO) among the Polish population.
Current eye research - 1 Mar 2009
Lacka Katarzyna, Paradowska Agnieszka, Gasinska Teresa, Soszynska Joanna, Wichary Hanna, Kramer Lucyna, Lacki Jan K
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate whether the IL-1beta gene could be a genetic marker of the thyroid-associated ophthalmopathy (TAO) development. MATERIALS AND METHODS: The IL-1beta gene polymorphisms at -511 and +3953 regions in 117 TAO patients of Polish origin (ATA/NOSPECS class III or greater) and in 106 controls were studied. RESULTS: We found no significant differences in the frequencies of...
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