Article
Escitalopram efficacy in depression: a cross-ethnicity examination of the serotonin transporter promoter polymorphism.
Journal of clinical psychopharmacology - 1 Oct 2014
Bousman Chad A, Sarris Jerome, Won Eun-Soo, Chang Hun-Soo, Singh Ajeet, Lee Hwa-Young, Ham Byung-Joo, Tan Chay-Hoon, Lee Min-Soo, Ng Chee H
Abstract excerpt
Current evidence suggests that polymorphism in the serotonin transporter gene (5-HTTLPR) predicts antidepressant efficacy in whites but less so in Asians. However, it is not clear whether this effect can be observed for specific types of antidepressant drugs. White (n = 47) and Korean (n = 118) participants with major depressive disorder were treated with escitalopram and assessed over 8 weeks. Among those with...
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