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Article

Characterization of dengue virus entry into HepG2 cells

4 Feb 2009

Abstract excerpt

BACKGROUND: Despite infections by the dengue virus being a significant problem in tropical and sub-tropical countries, the mechanism by which the dengue virus enters into mammalian cells remains poorly described. METHODS: A combination of biochemical inhibition, dominant negative transfection of Eps15 and siRNA mediated gene silencing was used to explore the entry mechanism of dengue into HepG2 cells. RESULTS:...

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PMID: 19272179
DOI: 10.1186/1423-0127-16-17

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