Article
Dynamin- and clathrin-dependent endocytosis in African swine fever virus entry.
Journal of virology - 1 Feb 2010
Hernaez Bruno, Alonso Covadonga
Abstract excerpt
African swine fever virus (ASFV) is a large DNA virus that enters host cells after receptor-mediated endocytosis and depends on acidic cellular compartments for productive infection. The exact cellular mechanism, however, is largely unknown. In order to dissect ASFV entry, we have analyzed the major endocytic routes using specific inhibitors and dominant negative mutants and analyzed the consequences for ASFV...
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