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Article

Internalization and Propagation of the Dengue Virus in Human Hepatoma (HepG2) Cells

1 Jan 2004

Abstract excerpt

OBJECTIVES: This study sought to undertake a comparative analysis of the internalization and propagation of all four dengue serotypes in a single cell line of human liver origin, HepG2. METHODS: Virus production after infection was determined by the plaque assay technique. Internalization profiles were determined by incubating virus and cells on ice and then raising the temperature for various times. The...

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PMID: 15192271
DOI: 10.1159/000077830

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