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New Developments in Antiepileptic Drug Resistance: An Integrative View

1 Mar 2009

Abstract excerpt

Current theories on drug resistance in epilepsy include the drug transporter hypothesis, the drug target hypothesis, and a novel approach called the inherent severity model of epilepsy, which posits that the severity of the disease determines its relative response to medication. Valuable as each of these hypotheses is, none is currently a stand-alone theory that is able to convincingly explain drug resistance in...

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PMID: 19421380
DOI: 10.1111/j.1535-7511.2008.01289.x

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