Article
Acetylcholine receptors direct rapsyn clusters to the neuromuscular synapse in zebrafish.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 16 Jun 2004
Ono Fumihito, Mandel Gail, Brehm Paul
Abstract excerpt
Clustering of nicotinic muscle acetylcholine receptors (AChRs) requires association with intracellular rapsyn, a protein with an intrinsic ability to self-cluster. Previous studies on sofa potato (sop), an AChR null line of zebrafish, have suggested that AChRs may play an active role in subsynaptic localization of rapsyn clusters. To test this proposal directly, we identified and cloned the gene responsible for...
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