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Article

Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk.

Cancer causes & control : CCC - 1 Dec 2008

Tse Darren, Zhai Rihong, Zhou Wei, Heist Rebecca S, Asomaning Kofi, Su Li, Lynch Thomas J, Wain John C, Christiani David C, Liu Geoffrey

Abstract excerpt

PURPOSE: Functional variation in DNA repair capacity through single nucleotide polymorphisms (SNPs) of key repair genes is associated with a higher risk of developing various types of cancer. Studies have focused on the nucleotide excision repair (NER) and base excision repair (BER) pathways. We...

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Source

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Identifiers

PMID: 18478337
DOI: 10.1007/s10552-008-9171-4
PMCID: PMC3106102

Genes

ERCC1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18478337-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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