Article
Protein 4.2 Komatsu (D175Y) associated with the lack of interaction with ankyrin in human red blood cells.
Blood cells, molecules & diseases - 1 Jan 2000
Su Yang, Ding Yu, Jiang Ming, Hu Xiaojian, Zhang Zhihong
Abstract excerpt
Membrane skeletal proteins play an important role in regulating the shape and function of the human red blood cell. Protein 4.2 interacts with cytoplasmic domain of band 3 (CDB3) and ankyrin for association between the skeleton network and the membrane. The deficiency of protein 4.2 may result in hereditary spherocytosis. In order to explore the molecular mechanism of the linkage of protein 4.2 Komatsu (D175Y)...
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