Article
Gamma irradiation alters the phenotype and function of CD4+CD25+ regulatory T cells.
Cell biology international - 1 May 2009
Cao Mengde, Cabrera Roniel, Xu Yiling, Liu Chen, Nelson David
Abstract excerpt
To examine the effects of gamma irradiation on Tregs, changes in phenotype and suppression function in Tregs treated with or without gamma ray were analyzed. Purified CD4(+)CD25(+) regulatory T cells were irradiated at different dosages with a (137)Cs source gamma ray at 4.8 Gy/min. After culture, the phenotype and function changes were determined by flow cytometry and [(3)H]-thymidine incorporation,...
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