Article
Influence of genotypes and precore mutations on fulminant or chronic outcome of acute hepatitis B virus infection.
Hepatology (Baltimore, Md.) - 1 Aug 2006
Ozasa Atsushi, Tanaka Yasuhito, Orito Etsuro, Sugiyama Masaya, Kang Jong-Hon, Hige Shuhei, Kuramitsu Tomoyuki, Suzuki Kazuyuki, Tanaka Eiji, Okada Shunichi, Tokita Hajime, Asahina Yasuhiro, Inoue Kazuaki, Kakumu Shinichi, Okanoue Takeshi, Murawaki Yoshikazu, Hino Keisuke, Onji Morikazu, Yatsuhashi Hiroshi, Sakugawa Hiroshi, Miyakawa Yuzo, Ueda Ryuzo, Mizokami Masashi
Abstract excerpt
The outcome of acute hepatitis B virus (HBV) infection is variable, influenced by host and viral factors. From 1982 through 2004, 301 patients with acute HBV infection entered a multi-center cross-sectional study in Japan. Patients with fulminant hepatitis (n = 40) were older (44.7 +/- 16.3 vs. 36.0 +/- 14.3 years, P < .0017), less predominantly male (43% vs. 71%, P = .0005), less positive for hepatitis B e...
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