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Article

Genetic and functional characterization of the mouse Trl3 locus in defense against tuberculosis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2009

Marquis Jean-François, Lacourse Ronald, Ryan Lynn, North Robert J, Gros Philippe

Abstract excerpt

The genetic control of susceptibility to tuberculosis in DBA/2J and C57BL/6J mice is complex and influenced by at least four tuberculosis resistance loci (Trl1-Trl4). To further study the Trl3 and Trl4 loci, we have created congenic mouse lines D2.B6-Chr7 and D2.B6-Chr19, in which resistant B6-de...

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Share to Chromosomal Proteins, Non-Histone
Share to Gene Expression Regulation
Share to Immunity, Innate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Congenic

Share to Mice, Inbred DBA

Share to Mycobacterium tuberculosis

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Share to Tuberculosis, Pulmonary

Source

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Identifiers

PMID: 19265154
DOI: 10.4049/jimmunol.0802094
PMCID: PMC4301439

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19265154-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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