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Article

The immunogenetics of Psoriasis: A comprehensive review.

Journal of autoimmunity - 1 Nov 2015

Harden Jamie L, Krueger James G, Bowcock Anne M

Abstract excerpt

Psoriasis vulgaris is a common, chronic inflammatory skin disease with a complex etiology involving genetic risk factors and environmental triggers. Here we describe the many known genetic predispositions of psoriasis with respect to immune genes and their encoded pathways in psoriasis susceptibility. These genes span an array of functions that involve antigen presentation (HLA-Cw6, ERAP1, ERAP2, MICA), the IL-23...

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Share to Antigen Presentation
Share to Genetic Loci
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

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Source

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Identifiers

PMID: 26215033
DOI: 10.1016/j.jaut.2015.07.008
PMCID: PMC4628849

Genes

CARD14
ERAP1
ERAP2
IFIH1
JAK2
MICA
NFKBIA
REL
RUNX1
RUNX3
SOCS1
STAT3
TAGAP
TNFAIP3
TNIP1
TYK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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