Article
Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Apr 2009
Hanasaki Hiroko, Takemura Yukihiro, Fukuo Keisuke, Ohishi Mitsuru, Onishi Miyuki, Yasuda Osamu, Katsuya Tomohiro, Awata Nobuhisa, Kato Norihiro, Ogihara Toshio, Rakugi Hiromi
Abstract excerpt
A growing body of evidence has shown that Fas-mediated apoptosis is involved in atherosclerosis progression. Recent studies have revealed that a single nucleotide polymorphism (SNP) in the Fas promoter region (-670G/A) influences Fas expression. Here, we investigated whether -670G/A SNP influences the incidence of myocardial infarction (MI) by examining a comparison between MI patients (n=154) and control...
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