Article
Functional SNP in an Sp1-binding site of AGTRL1 gene is associated with susceptibility to brain infarction.
Human molecular genetics - 15 Mar 2007
Hata Jun, Matsuda Koichi, Ninomiya Toshiharu, Yonemoto Koji, Matsushita Tomonaga, Ohnishi Yozo, Saito Susumu, Kitazono Takanari, Ibayashi Setsuro, Iida Mitsuo, Kiyohara Yutaka, Nakamura Yusuke, Kubo Michiaki
Abstract excerpt
Brain infarction is one of the common causes of death and also a major cause of severe disability. To identify a gene(s) susceptible to brain infarction, we performed a large-scale association study of Japanese patients with brain infarction, using 52608 gene-based single nucleotide polymorphism (SNP) markers. Comparison of allele frequencies between 1112 cases with brain infarction and age- and sex-matched...
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