Article
Genetic variant of the p22PHOX component of NADPH oxidase C242T and the incidence of gastric cancer in Japan.
Hepato-gastroenterology - 1 Jan 2000
Tahara Tomomitsu, Arisawa Tomiyasu, Shibata Tomoyuki, Nakamura Masakatsu, Wang Fangyu, Yoshioka Daisuke, Okubo Masaaki, Maruyama Naoko, Kamano Tashiaki, Kamiya Yoshio, Nakamura Masahiko, Fujita Hiroshi, Nagasaka Mitsuo, Iwata Masami, Takahama Kazuya, Watanabe Makoto, Yamashita Hiromi, Nakano Hiroshi, Hirata Ichiro
Abstract excerpt
BACKGROUND/AIMS: Reactive oxygen species has been implicated in the development of gastric cancer. NADPH oxidase, a major source of superoxide generation play a critical role in H. pylori related gastric inflammation. We aimed to clarify the effect of C242T polymorphism of p22PHOX, an essential component of NADPH oxidase on the risk of gastric cancer, gastric ulcer and duodenal ulcer in a Japanese population....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.