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Article

Clinical significance of SOD2 and GSTP1 gene polymorphisms in Chinese patients with gastric cancer.

Cancer - 15 Nov 2012

Xu Zhi, Zhu Haixia, Luk John M, Wu Dongmei, Gu Dongying, Gong Weida, Tan Yongfei, Zhou Jianwei, Tang Jinhai, Zhang Zhengdong, Wang Meilin, Chen Jinfei

Abstract excerpt

BACKGROUND: Excessive reactive oxygen species (ROS) accumulation is a common phenomenon in carcinogenesis. However, the rationale behind ROS involvement in gastric cancer is unclear. In this study, the authors investigated the clinical significance of the single nucleotide polymorphisms (SNPs) of 2 ROS metabolic process-related genes: superoxide dismutase 2 (SOD2) and glutathione S-transferase π (GSTP1). METHODS:...

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Source

Identifiers

PMID: 22517484
DOI: 10.1002/cncr.27599

Genes

GSTP1
SOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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