Article
An association between polymorphism of the NADH/NADPH oxidase p22phox (phagocyte oxidase) subunit and aging in Turkish population.
Aging clinical and experimental research - 1 Oct 2013
Kayaaltı Zeliha, Kaya Dilek, Bacaksız Ayşegül, Söylemez Esma, Söylemezoğlu Tülin
Abstract excerpt
BACKGROUND AND AIMS: Aging is a complex and multifactorial process that is stimulated by a number of factors including genes and life-style. It is thought that the production of reactive oxygen species (ROS) in the face of antioxidant enzymes and molecules is related to aging and age-related diseases. NAD(P)H oxidase system is the predominant cellular source of ROS, and p22phox, the major component of that...
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