Article
Increased levels of cocaine and amphetamine regulated transcript in two animal models of depression and anxiety.
Neurobiology of disease - 1 May 2009
Wiehager Sara, Beiderbeck Daniela I, Gruber Susanne H M, El-Khoury Aram, Wamsteeker Jackie, Neumann Inga D, Petersén Asa, Mathé Aleksander A
Abstract excerpt
The neurobiological bases of mood disorders remain elusive but both monoamines and neuropeptides may play important roles. The neuropeptide cocaine and amphetamine regulated transcript (CART) was shown to induce anxiety-like behavior in rodents, and mutations in the human CART gene are associated...
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