Article
Association of incretin receptors genetic polymorphisms with type 2 diabetes mellitus in Egyptian patients.
The journal of gene medicine - 1 Sept 2017
Shalaby Sally M, Zidan Haidy E, Shokry Amira, Saeed Jehan, El-Sokkary Rehab H
Abstract excerpt
BACKGROUND: Incretins have opened a new era in type 2 diabetes mellitus (T2DM) pathogenesis. The present study aimed to assess whether there is an association between GIPR rs2302382, GIPR rs1800437 and GLP-1R rs367543060 polymorphisms with T2DM or not and also to determine the effect of these polymorphisms on gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) levels. METHODS: One hundred and...
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