Article
Common variants of GIP are associated with visceral fat accumulation in Japanese adults.
American journal of physiology. Gastrointestinal and liver physiology - 1 Dec 2014
Nakayama Kazuhiro, Watanabe Kazuhisa, Boonvisut Supichaya, Makishima Saho, Miyashita Hiroshi, Iwamoto Sadahiko
Abstract excerpt
Animal studies have demonstrated that glucose-dependent insulinotropic polypeptide (GIP) and GIP receptor (GIPR) contribute to the etiology of obesity. In humans, genomewide association studies have identified single nucleotide polymorphisms (SNPs) in the GIPR gene that are strongly associated with body mass index (BMI); however, it is not clear whether genetic variations in the GIP gene are involved in the...
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