Article
A pilot genome-wide association study meta-analysis of gastroparesis.
United European gastroenterology journal - 1 Oct 2023
Tavares Leticia Camargo, Zheng Tenghao, Kwicklis Madeline, Mitchell Emily, Pandit Anita, Pullapantula Suraj, Bernard Cheryl, Teder-Laving Maris, Marques Francine Z, Esko Tonu, Kuo Braden, Shulman Robert J, Chumpitazi Bruno P, Koch Kenneth L, Sarosiek Irene, Abell Thomas L, McCallum Richard W, Parkman Henry P, Pasricha Pankaj J, Hamilton Frank A, Tonascia James, Zawistowski Matthew, Farrugia Gianrico, Grover Madhusudan, D'Amato Mauro
Abstract excerpt
BACKGROUND: Gastroparesis (GP) is characterized by delayed gastric emptying in the absence of mechanical obstruction. OBJECTIVE: Genetic predisposition may play a role; however, investigation at the genome-wide level has not been performed. METHODS: We carried out a genome-wide association study (GWAS) meta-analysis on (i) 478 GP patients from the National Institute of Diabetes and Digestive and Kidney Diseases...
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