Article
The association of genetically determined serum glycine with cardiovascular risk in East Asians.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 7 Jun 2021
Chang Xuling, Wang Ling, Guan Shou Ping, Kennedy Brian K, Liu Jianjun, Khor Chiea-Chuen, Low Adrian F, Chan Mark Yan-Yee, Yuan Jian-Min, Koh Woon-Puay, Friedlander Yechiel, Dorajoo Rajkumar, Heng Chew-Kiat
Abstract excerpt
BACKGROUND AND AIMS: Glycine is involved in a wide range of metabolic pathways and increased circulating glycine is associated with reduced risk of cardio-metabolic diseases in Europeans but the genetic association between circulating glycine and cardiovascular risk is largely unknown in East Asians. METHODS AND RESULTS: We conducted a genome-wide association study (GWAS) in Singaporean Chinese participants and...
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