Article
Candida albicans RFX2 encodes a DNA binding protein involved in DNA damage responses, morphogenesis, and virulence.
Eukaryotic cell - 1 Apr 2009
Hao Binghua, Clancy Cornelius J, Cheng Shaoji, Raman Suresh B, Iczkowski Kenneth A, Nguyen M Hong
Abstract excerpt
We previously showed that Candida albicans orf19.4590, which we have renamed RFX2, expresses a protein that is reactive with antibodies in persons with candidiasis. In this study, we demonstrate that C. albicans RFX2 shares some functional redundancy with Saccharomyces cerevisiae RFX1. Complementation of an S. cerevisiae rfx1 mutant with C. albicans RFX2 partially restored UV susceptibility and the repression of...
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