Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

American journal of physiology. Heart and circulatory physiology - 1 May 2009

Gomez R Ariel, Pentz Ellen Steward, Jin Xuan, Cordaillat Magali, Sequeira Lopez Maria Luisa S

Abstract excerpt

The mechanisms that govern the identity of renin cells are not well understood. We and others have identified cAMP as an important pathway in the regulation of renin synthesis and release. Recently, experiments in cells from the renin lineage led us to propose that acquisition and maintenance of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Lineage
Share to CREB-Binding Protein
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to E1A-Associated p300 Protein

Share to Integrases

Share to Kidney

Share to Organogenesis

Source

Open in PubMed Open full text

Identifiers

PMID: 19252086
DOI: 10.1152/ajpheart.01266.2008
PMCID: PMC2685333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19252086-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.PMID 19252086Read ↗

Histone acetyl transferases CBP and p300 are necessary for maintenance of renin cell identity and transformation of smooth muscle cells to the renin phenotype.Semantic proximity Read ↗

Transcriptional regulator RBP-J regulates the number and plasticity of renin cells.Semantic proximity Read ↗

Renin Cells, the Kidney, and Hypertension.Semantic proximity Read ↗

The renin phenotype: roles and regulation in the kidney.Semantic proximity Read ↗

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.Semantic proximity Read ↗

Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation.Semantic proximity Read ↗

Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened.Semantic proximity Read ↗

Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells.Semantic proximity Read ↗

A single nucleotide mutation in the mouse renin promoter disrupts blood pressure regulation.Semantic proximity Read ↗

Renin cells with defective Gsα/cAMP signaling contribute to renal endothelial damageSemantic proximity Read ↗

Zebrafish mesonephric renin cells are functionally conserved and comprise two distinct morphological populations.Semantic proximity Read ↗

Is histone acetylation the most important physiological function for CBP and p300?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.