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Article

Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth.

The Journal of biological chemistry - 12 Jun 2009

Sämann Julia, Hegermann Jan, von Gromoff Erika, Eimer Stefan, Baumeister Ralf, Schmidt Enrico

Abstract excerpt

Mutations in two genes encoding the putative kinases LRRK2 and PINK1 have been associated with inherited variants of Parkinson disease. The physiological role of both proteins is not known at present, but studies in model organisms have linked their mutants to distinct aspects of mitochondrial dy...

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Identifiers

PMID: 19251702
DOI: 10.1074/jbc.M808255200
PMCID: PMC2713553

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19251702-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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