Article
Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row.
Science (New York, N.Y.) - 27 Feb 2009
Zhang Zunyi, Lan Yu, Chai Yang, Jiang Rulang
Abstract excerpt
Mammals have single-rowed dentitions, whereas many nonmammalian vertebrates have teeth in multiple rows. Neither the molecular mechanism regulating iterative tooth initiation nor that restricting mammalian tooth development in one row is known. We found that mice lacking the transcription factor...
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