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Homeobox code model of heterodont tooth in mammals revised

6 Sept 2019

Abstract excerpt

Heterodonty is one of the hallmarks of mammals. It has been suggested that, homeobox genes, differentially expressed in the ectomesenchyme of the jaw primordium along the distal-proximal axis, would determine the tooth classes (homeobox code model) based on mouse studies. Because mouse has highly specialized tooth pattern lacking canine and premolars (dental formula: 1003/1003, for upper and lower jaws,...

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PMID: 31492950
DOI: 10.1038/s41598-019-49116-x

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