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Article

Recognition of mannosylated ligands and influenza A virus by human surfactant protein D: contributions of an extended site and residue 343.

Biochemistry - 21 Apr 2009

Crouch Erika, Hartshorn Kevan, Horlacher Tim, McDonald Barbara, Smith Kelly, Cafarella Tanya, Seaton Barbara, Seeberger Peter H, Head James

Abstract excerpt

Surfactant protein D (SP-D) plays important roles in antiviral host defense. Although SP-D shows a preference for glucose/maltose, the protein also recognizes d-mannose and a variety of mannose-rich microbial ligands. This latter preference prompted an examination of the mechanisms of mannose recognition, particularly as they relate to high-mannose viral glycans. Trimeric neck plus carbohydrate recognition...

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Source

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Identifiers

PMID: 19249874
DOI: 10.1021/bi8022703
PMCID: PMC2720784

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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