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Article

Multimerization of surfactant protein D, but not its collagen domain, is required for antiviral and opsonic activities related to influenza virus.

Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 2008

White Mitchell, Kingma Paul, Tecle Tesfaldet, Kacak Nilgun, Linders Bruce, Heuser John, Crouch Erika, Hartshorn Kevan

Abstract excerpt

Surfactant protein D (SP-D) plays important roles in the initial innate defense against influenza A virus (IAV). The collagen domain of SP-D is probably critical for its homeostatic functions in vivo and has been implicated in the modulation of macrophage responses to SP-D-ligand complexes. For t...

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Source

Identifiers

PMID: 19017984
DOI: 10.4049/jimmunol.181.11.7936

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19017984-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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