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Article

Multimeric and trimeric subunit SP-D are interconvertible structures with distinct ligand interaction.

Molecular immunology - 1 Sept 2009

Sorensen Grith L, Hoegh Silje V, Leth-Larsen Rikke, Thomsen Theresa H, Floridon Charlotte, Smith Kelly, Kejling Karin, Tornoe Ida, Crouch Erika C, Holmskov Uffe

Abstract excerpt

Surfactant protein-D (SP-D) is a calcium dependent lectin in the innate immune system that facilitates clearance of microbes. The protein is associated with mucosal surfaces, and also found in bronchoalveolar lavage, serum and amniotic fluid. Human SP-D includes trimeric subunits and multimeric assemblies of trimeric subunits, which are stabilized by N-terminal interchain disulfide crosslinks. An N-terminal...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19577304
DOI: 10.1016/j.molimm.2009.06.005

Genes

LTA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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