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Article

Ligand specificity of human surfactant protein D: expression of a mutant trimeric collectin that shows enhanced interactions with influenza A virus.

The Journal of biological chemistry - 29 Apr 2005

Crouch Erika, Tu Yizheng, Briner David, McDonald Barbara, Smith Kelly, Holmskov Uffe, Hartshorn Kevan

Abstract excerpt

Surfactant protein D is a pattern recognition molecule that plays diverse roles in immune regulation and anti-microbial host defense. Its interactions with known ligands are calcium-dependent and involve binding to the trimeric, C-type carbohydrate recognition domain. Surfactant protein D preferentially binds to glucose and related sugars. However, CL-43, a bovine serum lectin, which evolved through duplication...

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Identifiers

PMID: 15711012
DOI: 10.1074/jbc.M413932200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ligand specificity of human surfactant protein D: expression of a mutant trimeric collectin that shows enhanced interactions with influenza A virus.PMID 15711012Read ↗

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