Article
Recombinant SP-D carbohydrate recognition domain is a chemoattractant for human neutrophils.
The American journal of physiology - 1 Jan 1999
Cai G Z, Griffin G L, Senior R M, Longmore W J, Moxley M A
Abstract excerpt
Human pulmonary surfactant protein D (SP-D) is a collagenous C-type lectin with high binding specificity to alpha-D-glucosyl residues. It is composed of four regions: a short NH2-terminal noncollagen sequence, a collagenous domain, a short linking domain ("neck" region), and a COOH-terminal carbohydrate recognition domain (CRD). Previous studies demonstrated that SP-D is chemotactic for inflammatory cells. To...
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