Article
Testing the association of novel meta-analysis-derived diabetes risk genes with type II diabetes and related metabolic traits in Asian Indian Sikhs.
Journal of human genetics - 1 Mar 2009
Sanghera Dharambir K, Been Latonya, Ortega Lyda, Wander Gurpreet S, Mehra Narinder K, Aston Christopher E, Mulvihill John J, Ralhan Sarju
Abstract excerpt
A recent meta-analysis on three genome-wide association (GWA) scans identified six loci (NOTCH2, THADA, ADAMTS9, JAZF1, CDC123/CAMKID and TSPAN8/LGRS) highly associated with type II diabetes (T2D) in Caucasians. This investigation seeks to confirm this association with diabetes and related metabolic traits in Khatri Sikh diabetics of North India. We genotyped highly significant variants from each locus in a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
