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Rapid Detection of Toxigenic Strains of <i>Clostridium difficile</i> in Diarrheal Stools by Real-Time PCR

26 Feb 2009

Abstract excerpt

Clostridium difficile is the major causative agent of nosocomial diarrhea and pseudomembranous colitis. The pathogenicity of C. difficile is related to the production of the toxins TcdA and TcdB. Currently the “gold standard” for the diagnosis of C. difficile-associated infections (CDI) is the cytotoxicity assay. However, this method is time-consuming and labor-intensive and requires an incubation of at least 24...

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PMID: 19244461
DOI: 10.1128/jcm.00309-09

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