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Article

CD4 T cells mediate killing during persistent gammaherpesvirus 68 infection.

Journal of virology - 1 May 2009

Stuller Kathleen A, Flaño Emilio

Abstract excerpt

CD4 T cells are critical for the control of gammaherpesvirus persistence, but their direct effector mechanisms of virus control in vivo are still poorly understood. In this study, we use murine gammaherpesvirus 68 (gammaHV68) in in vitro and in vivo cytotoxicity assays to show CD4-dependent killing of gammaHV68-loaded cells in mice persistently infected with gammaHV68. Our results underscore the cytotoxic...

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Identifiers

PMID: 19244319
DOI: 10.1128/JVI.02240-08
PMCID: PMC2668489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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