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Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection

9 Nov 2018

Abstract excerpt

The two human gammaherpesviruses, Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV), can cause aggressive forms of cancer. These herpesviruses are strictly host specific, and therefore the homolog murine gammaherpesvirus 68 (MHV68) is a widely used model to obtainin vivoinsights into the interaction between these two gammaherpesviruses and their host. Like EBV and KSHV, MHV68 establishes...

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PMID: 30429335
DOI: 10.1128/jvi.01173-18

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