Article
Cytotoxic CD4 T cells in antiviral immunity.
Journal of biomedicine & biotechnology - 1 Jan 2011
Marshall Nikki B, Swain Susan L
Abstract excerpt
CD4 T cells that acquire cytotoxic phenotype and function have been repeatedly identified in humans, mice, and other species in response to many diverse pathogens. Since CD4 cytotoxic T cells are able to recognize antigenic determinants unique from those recognized by the parallel CD8 cytotoxic T cells, they can potentially contribute additional immune surveillance and direct effector function by lysing infected...
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