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Article

Polymorphisms of the MDR1 Gene in the Czech Population

1 Jan 2006

Abstract excerpt

There exists a marked inter-individual variability of P-glycoprotein expression and activity, which can be of clinical importance due to the large number of drugs that are substrates for the transporter. Previously identified polymorphisms in the MDR1 gene belong to important factors causing this phenomenon. Our aim was to investigate the frequency of major functional SNPs of the MDR1 gene coding for...

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PMID: 17184596
DOI: 10.14712/fb2006052060184

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