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Article

Defective IL-10 production in severe phenotypes of Crohn's disease.

Journal of leukocyte biology - 1 May 2009

Correa Ismael, Veny Marisol, Esteller Miriam, Piqué Josep M, Yagüe Jordi, Panés Julián, Salas Azucena

Abstract excerpt

Loss of tolerance toward commensal bacteria has been invoked as a mechanism for Crohn's disease. IL-10 is a key anti-inflammatory cytokine that plays a role in induction and maintenance of tolerance. The aim of this study is to determine IL-10 production in response to bacterial components in Crohn's disease patients, who were classified according to their phenotypes as stricturing, penetrating, or inflammatory....

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Source

Identifiers

PMID: 19237638
DOI: 10.1189/jlb.1108698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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