Article
Array-based genotyping in S.cerevisiae using semi-supervised clustering.
Bioinformatics (Oxford, England) - 15 Apr 2009
Bourgon Richard, Mancera Eugenio, Brozzi Alessandro, Steinmetz Lars M, Huber Wolfgang
Abstract excerpt
MOTIVATION: Microarrays provide an accurate and cost-effective method for genotyping large numbers of individuals at high resolution. The resulting data permit the identification of loci at which genetic variation is associated with quantitative traits, or fine mapping of meiotic recombination, which is a key determinant of genetic diversity among individuals. Several issues inherent to short oligonucleotide...
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