Article
Algorithms for large-scale genotyping microarrays.
Bioinformatics (Oxford, England) - 12 Dec 2003
Liu Wei-mn, Di Xiaojun, Yang Geoffrey, Matsuzaki Hajime, Huang Jing, Mei Rui, Ryder Thomas B, Webster Teresa A, Dong Shoulian, Liu Guoying, Jones Keith W, Kennedy Giulia C, Kulp David
Abstract excerpt
MOTIVATION: Analysis of many thousands of single nucleotide polymorphisms (SNPs) across whole genome is crucial to efficiently map disease genes and understanding susceptibility to diseases, drug efficacy and side effects for different populations and individuals. High density oligonucleotide microarrays provide the possibility for such analysis with reasonable cost. Such analysis requires accurate, reliable...
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