Article
Rplp1 bypasses replicative senescence and contributes to transformation.
Experimental cell research - 1 May 2009
Artero-Castro A, Kondoh H, Fernández-Marcos P J, Serrano M, Ramón y Cajal S, Lleonart M E
Abstract excerpt
To determine whether genes expressed by embryonic stem cells have a proliferative effect in primary cells, primary mouse embryonic fibroblasts were infected with an ES cell cDNA library. This led to identification of the ribosomal protein, Rplp1, a member of the P group of ribosomal proteins, whose putative role for bypassing replicative senescence in MEFs was investigated. Our results show that Rplp1 produces a...
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